Description

4-(2-Fluoroethoxy)Benzene-1-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative, a critical building block in advanced organic synthesis. Its value lies in its ability to introduce the sulfonamide functional group under mild conditions, enabling the creation of complex molecules with tailored properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel sulfonamide-based drug candidates, including potential enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides that require the sulfonamide pharmacophore.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes for studying enzyme function and protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	4-(2-Fluoroethoxy)Benzene-1-Sulfonyl Chloride
CAS No.	264624-26-2
Molecular Formula	C8H8ClFO3S
Molecular Weight	238.66 g/mol
Synonyms	1-(2-Fluoroethoxy)-4-(chlorosulfonyl)benzene; p-(2-Fluoroethoxy)benzenesulfonyl chloride; 4-(2-Fluoroethoxy)benzenesulfonyl chloride; 2-Fluoroethyl 4-(chlorosulfonyl)phenyl ether; Benzenesulfonyl chloride, 4-(2-fluoroethoxy)-; 264624-26-2
EINECS	Contact for details

Quality Control

Our 4-(2-Fluoroethoxy)Benzene-1-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the stringent requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.