Description

2(1H)-Pyrimidinone, 4-Amino-1-(2-Propynyl)- (9Ci) is a specialized heterocyclic organic compound featuring a pyrimidinone core functionalized with amino and propargyl groups. This unique structure makes it a valuable high-purity building block for advanced chemical synthesis, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the life sciences sector for creating novel active pharmaceutical ingredients (APIs) and other biologically active molecules.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly those targeting specific enzymatic pathways.
• Bioconjugation Chemistry: Utilized in click chemistry applications due to the presence of the alkyne (propynyl) group, enabling efficient coupling with azide-functionalized molecules for labeling or creating bioconjugates.
• Agrochemical Research: Serves as a core structure for developing novel herbicides, fungicides, or plant growth regulators.
• Material Science: Potential monomer or cross-linking agent in the synthesis of specialty polymers with tailored properties.
• Chemical Biology Probe Development: Used to create molecular probes for studying biological processes and target identification.

Basic Information

Product Name	2(1H)-Pyrimidinone, 4-Amino-1-(2-Propynyl)- (9Ci)
CAS No.	264611-42-9
Molecular Formula	C7H7N3O
Molecular Weight	149.15 g/mol
Synonyms	4-Amino-1-(prop-2-yn-1-yl)pyrimidin-2(1H)-one; 4-Amino-1-propargyl-1H-pyrimidin-2-one; 1-Propargyl-4-aminopyrimidin-2(1H)-one; 4-Amino-1-(2-propynyl)-2(1H)-pyrimidinone; 4-Amino-1-(prop-2-ynyl)pyrimidin-2(1H)-one; 4-Amino-1-(prop-2-ynyl)-1H-pyrimidin-2-one; 4-Amino-1-(2-propynyl)pyrimidin-2(1H)-one
EINECS	Contact for details

Quality Control

Our production of 2(1H)-Pyrimidinone, 4-Amino-1-(2-Propynyl)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry for verification. While produced under quality management principles, this product is intended for research use and is not currently certified to USP/EP pharmacopeial standards unless specified.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.