Description

D-4-Cyanophenylalanine is a non-natural, side-chain modified aromatic amino acid derivative, specifically engineered for advanced research and development applications. This compound is a critical building block in medicinal chemistry, enabling the synthesis of novel peptides and small molecules with tailored properties. It is primarily utilized by pharmaceutical R&D teams, agrochemical scientists, and academic researchers focused on probing protein structure-function relationships and developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in protease inhibitor and receptor antagonist research.
• Peptide Synthesis: Used in Solid-Phase Peptide Synthesis (SPPS) to incorporate a cyano-functionalized phenylalanine residue, introducing unique electronic and steric properties into peptide sequences.
• Bioconjugation & Probe Development: Serves as a precursor for creating fluorescent or affinity probes to study biological systems, leveraging the reactivity of the cyano group.
• Agrochemical Research: Employed in the design and synthesis of new active ingredients with potential herbicidal or insecticidal activity.
• Material Science: Acts as a monomer or functional additive in the creation of specialized polymers and advanced materials.
• Academic & Biochemical Research: Used in studies of enzyme mechanisms, protein engineering, and as a non-canonical amino acid in synthetic biology.

Basic Information

Product Name	D-4-Cyanophenylalanine
CAS No.	263396-44-7
Molecular Formula	C10H10N2O2
Molecular Weight	190.20 g/mol
Synonyms	(R)-2-Amino-3-(4-cyanophenyl)propanoic acid; D-p-Cyanophenylalanine; D-4-CN-Phe; D-para-Cyanophenylalanine; (R)-4-Cyanophenylalanine; D-β-(4-Cyanophenyl)-alanine; Fmoc-D-4-cyanophenylalanine (precursor form); D-Phe(4-CN)-OH
EINECS	Contact for details

Quality Control

Our D-4-Cyanophenylalanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and specific impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Loss on Drying	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.