Description

4-Chloro-6-(1-Pyrrolidinyl)-2-Pyrimidinamine is a high-purity pyrimidine derivative, a crucial building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly in kinase inhibitor research and other small-molecule therapeutics.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Chemical Biology Probe Synthesis: Used to create molecular tools for studying biological pathways and target validation in life sciences.
• Material Science Research: A potential monomer or functional unit in the development of specialty polymers and advanced organic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke chemical synthesis projects.

Basic Information

Product Name	4-Chloro-6-(1-Pyrrolidinyl)-2-Pyrimidinamine
CAS No.	263276-45-5
Molecular Formula	C8H11ClN4
Molecular Weight	198.65 g/mol
Synonyms	2-Pyrimidinamine, 4-chloro-6-(1-pyrrolidinyl)-; 4-Chloro-6-pyrrolidin-1-ylpyrimidin-2-amine; 4-Chloro-6-(pyrrolidin-1-yl)pyrimidin-2-amine; 4-Chloro-6-(N-pyrrolidinyl)-2-aminopyrimidine; 4-Chloro-6-(1-pyrrolidinyl)-2-aminopyrimidine; 263276-45-5; 4-Chloro-6-pyrrolidin-1-yl-2-pyrimidinamine
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-(1-Pyrrolidinyl)-2-Pyrimidinamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.