Description

tert-Butyl 2-(2-Isobutyramido-6-oxo-1H-purin-9(6H)-yl)acetate is a high-purity, advanced pharmaceutical intermediate designed for critical synthesis pathways. This compound is valued for its role as a key building block in the development of novel active pharmaceutical ingredients (APIs), particularly in nucleoside and purine-based therapeutics. It is essential for research and manufacturing organizations in the pharmaceutical and biotechnology sectors seeking reliable, high-quality intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of purine-based drug candidates and nucleoside analogues.
• Antiviral Drug Research: Used in the development and scale-up of potential antiviral agents targeting specific viral enzymes.
• Oncology Therapeutics: Serves as a building block for experimental chemotherapeutic agents and targeted cancer therapies.
• Process Chemistry & Scale-Up: Employed in process research and development (PR&D) and pilot-scale manufacturing for route optimization.
• Biochemical Research: Utilized in academic and industrial research to study enzyme inhibition and modulate biological pathways.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized compounds for clients.

Basic Information

Product Name	tert-Butyl 2-(2-Isobutyramido-6-oxo-1H-purin-9(6H)-yl)acetate
CAS No.	263254-55-3
Molecular Formula	C16H23N5O4
Molecular Weight	349.39 g/mol
Synonyms	2-(2-Isobutyramido-6-oxo-1H-purin-9(6H)-yl)acetic acid tert-butyl ester; 9H-Purin-9-acetic acid, 2-(2-methyl-1-oxopropoxy)-6-oxo-, 1,1-dimethylethyl ester; tert-Butyl N-(6-oxo-9H-purin-2-yl)isobutyrylglycinate; 263254-55-3; tert-Butyl 2-(2-isobutyrylamino-6-oxopurin-9-yl)acetate
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 2-(2-Isobutyramido-6-oxo-1H-purin-9(6H)-yl)acetate adheres to stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure consistency and compliance with customer specifications. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting GMP-grade applications and regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccated environment to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.