Description

(E)-Methyl 4-(Benzyloxy)-2-((Dimethylamino)Methyleneamino)-5-Methoxybenzoate is a high-purity, advanced pharmaceutical intermediate with a complex molecular architecture. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in research and development pipelines. It is primarily sought by pharmaceutical manufacturers, contract research organizations (CROs), and fine chemical synthesis specialists working on next-generation therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of complex drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Research & Development (R&D): Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Active Pharmaceutical Ingredient (API) Synthesis: Integral to the production route of specific APIs, where its unique structure introduces essential pharmacophores.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing high-value, low-volume specialty chemicals.
• Process Chemistry Optimization: Used to develop and scale up efficient, cost-effective synthetic pathways for target molecules in pilot plants.

Basic Information

Product Name	(E)-Methyl 4-(Benzyloxy)-2-((Dimethylamino)Methyleneamino)-5-Methoxybenzoate
CAS No.	263149-09-3
Molecular Formula	C19H22N2O4
Molecular Weight	342.39 g/mol
Synonyms	Methyl (2E)-2-[(dimethylamino)methylideneamino]-4-(phenylmethoxy)-5-methoxybenzoate; 2-[(E)-(Dimethylamino)methyleneamino]-4-(benzyloxy)-5-methoxybenzoic acid methyl ester; 4-(Benzyloxy)-2-((dimethylamino)methyleneamino)-5-methoxybenzoic acid methyl ester; Benzoic acid, 4-(benzyloxy)-2-[(E)-(dimethylamino)methyleneamino]-5-methoxy-, methyl ester; (E)-Methyl 4-(benzyloxy)-2-((dimethylamino)methyleneamino)-5-methoxybenzoate; Methyl 4-(benzyloxy)-2-((dimethylamino)methyleneamino)-5-methoxybenzoate (E)-isomer
EINECS	Contact for details

Quality Control

Our (E)-Methyl 4-(Benzyloxy)-2-((Dimethylamino)Methyleneamino)-5-Methoxybenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.