Description

Pyrimidine, 2-Iodo-4-Methoxy- (9Ci) is a halogenated pyrimidine derivative, a versatile building block in advanced organic synthesis. This compound is valued for its iodine substituent, which facilitates key coupling reactions like Suzuki and Sonogashira cross-couplings, enabling the construction of complex heterocyclic systems. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for antiviral, anticancer, and CNS-targeted therapies.
• Agrochemical Research: Used to create novel pyrimidine-based herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a building block for organic semiconductors, liquid crystals, and photoactive polymers.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions (e.g., Suzuki, Stille, Sonogashira) to form new carbon-carbon bonds.
• Chemical Biology: Used in the synthesis of molecular probes and labeled compounds for biochemical and diagnostic research.
• Academic & R&D: A valuable reagent for methodological development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	Pyrimidine, 2-Iodo-4-Methoxy- (9Ci)
CAS No.	262353-35-5
Molecular Formula	C5H5IN2O
Molecular Weight	236.01 g/mol
Synonyms	2-Iodo-4-methoxypyrimidine; 4-Methoxy-2-iodopyrimidine; 2-Iodo-4-methoxy-1,3-diazine; 2-Iodo-4-methoxypyrimidine (9CI); 262353-35-5; 4-Methoxy-2-iodo-pyrimidine; Pyrimidine, 2-iodo-4-methoxy-
EINECS	Contact for details

Quality Control

Our Pyrimidine, 2-Iodo-4-Methoxy- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.