Description

4-Methyl-3-(trifluoromethyl)benzyl alcohol is a versatile fluorinated aromatic alcohol building block. This compound is valued for its unique trifluoromethyl-substituted benzyl structure, which imparts desirable properties such as enhanced lipophilicity and metabolic stability in advanced molecular frameworks. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances bioactivity.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance display technologies.
• Organic Electronic Materials: Employed in the development of novel organic semiconductors and charge-transport materials.
• Cross-Coupling Reactions: The benzyl alcohol moiety can be functionalized for use in Suzuki, Heck, and other palladium-catalyzed coupling reactions.
• Protecting Group Chemistry: Acts as a starting material for creating specialized protecting groups in complex multi-step organic syntheses.
• Fluorine Chemistry Research: An important compound for academic and industrial research into the effects of fluorine substitution on chemical reactivity and physical properties.

Basic Information

Product Name	4-Methyl-3-(trifluoromethyl)benzyl Alcohol
CAS No.	261952-15-2
Molecular Formula	C9H9F3O
Molecular Weight	190.16 g/mol
Synonyms	3-(Trifluoromethyl)-4-methylbenzyl Alcohol; (3-Trifluoromethyl-4-methylphenyl)methanol; α,α,α-Trifluoro-4-methyl-m-tolylmethanol; 4-Methyl-α,α,α-trifluoro-m-toluyl Alcohol; 1-[3-(Trifluoromethyl)-4-methylphenyl]methanol; 4-Methyl-3-trifluoromethylbenzenemethanol; Benzenemethanol, 3-(trifluoromethyl)-4-methyl-
EINECS	Contact for details

Quality Control

Our 4-Methyl-3-(trifluoromethyl)benzyl alcohol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.