Description

3-Chloro-2-Fluoro-5-(Trifluoromethyl)Phenol is a high-value fluorinated phenolic intermediate with a unique halogenated structure. This compound matters for its role as a critical building block in the synthesis of advanced agrochemicals and pharmaceuticals, where its specific substitution pattern imparts desirable biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the fine chemical, agrochemical, and pharmaceutical industries for creating novel active ingredients.

Application

• Agrochemical Intermediate: A key synthon for the development of next-generation herbicides, fungicides, and insecticides, leveraging the trifluoromethyl and halogen groups for enhanced efficacy and environmental profile.
• Pharmaceutical Building Block: Used in medicinal chemistry for the synthesis of drug candidates, particularly in areas requiring fluorinated aromatic systems to modulate bioavailability and binding affinity.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for advanced display technologies.
• Polymer Chemistry: Acts as a monomer or modifier in the production of specialty polymers with enhanced chemical resistance and thermal stability.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and as a protecting group or directing group in complex multi-step synthetic routes.

Basic Information

Product Name	3-Chloro-2-Fluoro-5-(Trifluoromethyl)Phenol
CAS No.	261763-12-6
Molecular Formula	C7H3ClF4O
Molecular Weight	214.55 g/mol
Synonyms	3-Chloro-2-fluoro-5-(trifluoromethyl)phenol; 2-Fluoro-3-chloro-α,α,α-trifluoro-p-cresol; 5-Trifluoromethyl-3-chloro-2-fluorophenol; Phenol, 3-chloro-2-fluoro-5-(trifluoromethyl)-; 261763-12-6; 3-Chloro-2-fluoro-α,α,α-trifluoro-p-cresol
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Fluoro-5-(Trifluoromethyl)Phenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.