Description

6-Chloro-2-Fluoro-3-Methylbenzyl Alcohol is a versatile fluorinated benzyl alcohol derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of halogen and methyl substituents, which enables precise molecular modifications for creating high-value intermediates. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring halogenated aromatic scaffolds.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides where the fluorine atom enhances bioactivity and metabolic stability.
• Liquid Crystal Materials: Used in the research and production of fluorinated liquid crystals for display technologies.
• Organic Electronic Materials: Serves as a starting material for synthesizing charge-transport materials or emissive layers in OLEDs.
• Cross-Coupling Reactions: The benzyl alcohol group can be functionalized for use in Suzuki, Heck, or other palladium-catalyzed cross-coupling reactions.
• Protecting Group Chemistry: Utilized in multi-step synthetic routes where the alcohol functionality requires temporary protection and deprotection.
• Chemical Research & Development: A valuable reagent for exploring new reaction methodologies and creating compound libraries for screening.

Basic Information

Product Name	6-Chloro-2-Fluoro-3-Methylbenzyl Alcohol
CAS No.	261762-84-9
Molecular Formula	C8H8ClFO
Molecular Weight	174.60 g/mol
Synonyms	(6-Chloro-2-fluoro-3-methylphenyl)methanol; 2-Fluoro-6-chloro-3-methylbenzyl alcohol; 1-(6-Chloro-2-fluoro-3-methylphenyl)methanol; Benzyl alcohol, 6-chloro-2-fluoro-3-methyl-; 261762-84-9; 6-Chloro-2-fluoro-m-tolylmethanol; 3-(Hydroxymethyl)-2-fluoro-6-chlorotoluene
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-Fluoro-3-Methylbenzyl Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.