Description

2-Pyrimidinecarboxylic Acid, 4-Bromo- (9Ci) is a high-purity brominated pyrimidine derivative, a crucial heterocyclic building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific substitution pattern enables precise molecular modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in kinase inhibitor and antiviral agent discovery.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators that require brominated heterocyclic cores.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of organic electronic materials and functional polymers where pyrimidine units are integral.
• Chemical Biology Probes: Utilized to develop molecular probes and labeled compounds for studying biological mechanisms and diagnostics.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up manufacturing under cGMP conditions.

Basic Information

Product Name	2-Pyrimidinecarboxylic Acid, 4-Bromo- (9Ci)
CAS No.	259810-39-4
Molecular Formula	C5H3BrN2O2
Molecular Weight	202.99 g/mol
Synonyms	4-Bromo-2-pyrimidinecarboxylic acid; 4-Bromopyrimidine-2-carboxylic acid; 2-Pyrimidinecarboxylic acid, 4-bromo-; 4-Bromo-2-carboxypyrimidine; 4-Bromopyrimidine-2-carboxylate; 259810-39-4; 4-Bromo-2-pyrimidinecarboxylic acid (9CI); 4-Bromopyrimidine-2-carboxylic acid (9CI)
EINECS	Contact for details

Quality Control

Our 2-Pyrimidinecarboxylic Acid, 4-Bromo- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials. This product is light-sensitive and should be stored away from light as indicated.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.