Description

(2S)-2-Amino-3-(2,3-Dimethylphenyl)Propanoic Acid is a non-natural, chiral amino acid derivative featuring a sterically hindered, dimethyl-substituted aromatic side chain. This structural motif makes it a valuable and sophisticated building block for the synthesis of complex organic molecules, particularly in pharmaceutical research and development. It is primarily utilized by medicinal chemists and process development scientists in the life sciences industry for creating novel peptide mimetics, enzyme inhibitors, and other bioactive compounds where precise stereochemistry and specific steric interactions are critical for activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and metabolic disorder targets.
• Peptidomimetic Design: Used to incorporate a rigid, hydrophobic aromatic group into peptide backbones to enhance metabolic stability, receptor selectivity, and membrane permeability.
• Asymmetric Synthesis: Serves as a starting material or auxiliary in catalytic asymmetric reactions to construct other chiral molecules with high enantiomeric purity.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds or molecular probes for studying enzyme mechanisms and protein-protein interactions.
• Agrochemical Research: Potential intermediate in the development of novel herbicides or plant growth regulators with specific chiral activity.
• Material Science: Can be used to synthesize novel monomers for specialty polymers, such as polyamides or liquid crystals, with tailored properties.

Basic Information

Item	Details
Product Name	(2S)-2-Amino-3-(2,3-Dimethylphenyl)Propanoic Acid
CAS No.	259726-55-1
Molecular Formula	C11H15NO2
Molecular Weight	193.24 g/mol
Synonyms	(S)-2-Amino-3-(2,3-dimethylphenyl)propanoic acid; (S)-2,3-Dimethyl-DL-phenylalanine; L-2,3-Dimethylphenylalanine; (S)-α-Amino-2,3-dimethylbenzenepropanoic acid; 2,3-Dimethyl-L-phenylalanine; (2S)-2-Amino-3-(2,3-dimethylphenyl)propionic acid; (S)-3-(2,3-Dimethylphenyl)alanine
EINECS	Contact for details

Quality Control

Our production of (2S)-2-Amino-3-(2,3-Dimethylphenyl)Propanoic Acid adheres to stringent internal quality standards to ensure batch-to-batch consistency and high chemical purity, essential for research and development applications. Each lot is fully characterized, with critical parameters including chiral purity (enantiomeric excess) and chemical purity being rigorously verified. A comprehensive Certificate of Analysis (COA) detailing identity, assay, impurity profile, and specific rotation is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent absorption of water vapor.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.