Description

Fospropofol Disodium (Aquavan) is a water-soluble prodrug of the widely used intravenous anesthetic propofol. This compound is designed to provide a more controlled and predictable onset of sedation, addressing key challenges in anesthetic management. It is primarily utilized in clinical and pharmaceutical research settings for the development of next-generation sedative-hypnotic agents. Global B2B clients in the pharmaceutical and fine chemical sectors source this material for advanced drug formulation and synthesis.

Application

• Pharmaceutical Intermediate: Key starting material or advanced intermediate in the synthesis of novel sedative-hypnotic drugs.
• Clinical Research: Used in preclinical and clinical studies to investigate improved pharmacokinetic profiles for anesthesia.
• Prodrug Development: Serves as a model compound in R&D for designing water-soluble prodrugs of poorly soluble active pharmaceutical ingredients (APIs).
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Biochemical Research: Utilized in studies exploring GABAA receptor modulation and mechanisms of intravenous anesthesia.

Basic Information

Product Name	Fospropofol Disodium (Aquavan)
CAS No.	258516-87-9
Molecular Formula	C13H19Na2O5P
Molecular Weight	356.23 g/mol
Synonyms	Aquavan; Fospropofol Disodium Salt; GPI 15715; 2,6-Diisopropylphenol phosphate disodium salt; Phosphonooxypropofol Disodium; Propofol phosphate disodium; Lusedra; Disodium (2,6-diisopropylphenoxy)methyl phosphate
EINECS	Contact for details

Quality Control

Our Fospropofol Disodium is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for research and development purposes. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our quality commitment ensures the material meets the stringent requirements of pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤2.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.