Description

Propanamide, n-[6-Amino-1-[(4-Chlorophenyl)Methyl]-3-Ethyl-1,2,3,4-Tetrahydro-2,4-Dioxo-5-Pyrimidinyl]-2-Methyl- is a high-purity, specialized organic compound with the CAS registry number 257939-29-0. This compound is a key pharmaceutical intermediate valued for its role in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development and production of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of proprietary drug candidates, particularly in oncology and antiviral research.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in multi-step synthetic routes to construct complex molecular frameworks for target APIs.
• Biochemical Research: Employed as a reference standard or a reagent in medicinal chemistry and pharmacology studies.
• Process Development & Scale-up: Utilized in optimizing synthetic pathways from laboratory to pilot and commercial production scales.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	Propanamide, n-[6-Amino-1-[(4-Chlorophenyl)Methyl]-3-Ethyl-1,2,3,4-Tetrahydro-2,4-Dioxo-5-Pyrimidinyl]-2-Methyl-
CAS No.	257939-29-0
Molecular Formula	C₁₇H₂₁ClN₄O₃
Molecular Weight	364.83 g/mol
Synonyms	2-Methyl-N-[6-amino-1-[(4-chlorophenyl)methyl]-3-ethyl-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl]propanamide; 257939-29-0; 1H-Pyrimidine-2,4-dione, 5-[(2-methyl-1-oxopropyl)amino]-1-[(4-chlorophenyl)methyl]-3-ethyl-6-amino-; 5-[(2-Methylpropanoyl)amino]-1-[(4-chlorophenyl)methyl]-3-ethyl-6-amino-1,2,3,4-tetrahydro-2,4-pyrimidinedione
EINECS	Contact for details

Quality Control

Our pharmaceutical-grade intermediate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting compliance with agreed specifications. Our quality commitment supports cGMP principles for use in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.