Description

H-Arg(Pbf)-Oall Hcl is a protected arginine derivative, specifically designed for solid-phase peptide synthesis (SPPS). This compound is critical for researchers and manufacturers requiring high-purity, sequence-specific peptide construction. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic laboratories engaged in the development of therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key building block for the controlled incorporation of arginine residues into peptide chains.
• Therapeutic Peptide Development: Used in the research and production of peptide-based drugs targeting various diseases.
• Bioconjugation and Labeling: Acts as an intermediate for creating peptide conjugates used in diagnostics and targeted drug delivery systems.
• Biochemical Research: Essential for studying protein-protein interactions, enzyme substrates, and receptor ligands where arginine plays a functional role.
• Antibiotic Peptide Mimetics: Employed in the synthesis of antimicrobial peptide analogs for novel antibiotic development.
• Vaccine Adjuvant Research: Used in the synthesis of peptide antigens and immunostimulatory sequences.

Basic Information

Product Name	H-Arg(Pbf)-Oall Hcl
CAS No.	257288-23-6
Molecular Formula	C₂₃H₃₆N₄O₆S • HCl
Molecular Weight	533.08 g/mol
Synonyms	Nα-Alloxycarbonyl-Nω-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine hydrochloride; Fmoc-Arg(Pbf)-OH (common precursor form); Alloc-Arg(Pbf)-OH • HCl; H-Arg(Pbf)-OAll • HCl; L-Arginine, N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N5-[[2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)sulfonyl]-, hydrochloride; Protected Arginine derivative; Pbf-Arg-OAll HCl
EINECS	Contact for details

Quality Control

Our H-Arg(Pbf)-Oall Hcl is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive peptide synthesis applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.