Description

4-Aminopyrimidine-5-Carbothioamide Hydrate is a versatile heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its bifunctional structure, featuring both an amino and a carbothioamide group on the pyrimidine core, which makes it a key precursor for the development of complex molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the creation of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of nucleoside analogs, kinase inhibitors, and other targeted therapeutic agents.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators due to its bioactive pyrimidine scaffold.
• Ligand Synthesis: Acts as a starting material for creating complex chelating ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Fine Chemical Manufacturing: Utilized as a specialized building block for producing high-value, custom-synthesized compounds for various industrial applications.

Basic Information

Product Name	4-Aminopyrimidine-5-Carbothioamide Hydrate
CAS No.	256525-68-5
Molecular Formula	C5H8N4OS • xH2O
Molecular Weight	156.16 (Anhydrous basis)
Synonyms	5-Carbamothioylpyrimidin-4-amine hydrate; 4-Amino-5-pyrimidinecarbothioamide hydrate; 5-Aminopyrimidine-4-carbothioamide hydrate; 4-Amino-5-thiocarbamoylpyrimidine hydrate; 5-Pyrimidinecarbothioamide, 4-amino-, hydrate; 4-APC hydrate
EINECS	Contact for details

Quality Control

Our 4-Aminopyrimidine-5-Carbothioamide Hydrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed batch-specific results are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.