Description

5-Fluoro-2-Iodoaniline is a halogenated aniline derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents, makes it a valuable precursor for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated and iodinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the halogen atoms can enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or precursor for the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form complex biaryl structures.
• Fluorine Chemistry: Utilized in medicinal chemistry to study the effects of fluorine substitution on pharmacokinetics and metabolic stability.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	5-Fluoro-2-Iodoaniline
CAS No.	255724-71-1
Molecular Formula	C6H5FIN
Molecular Weight	237.01 g/mol
Synonyms	2-Iodo-5-fluoroaniline; 5-Fluoro-2-iodobenzenamine; 1-Amino-5-fluoro-2-iodobenzene; Benzenamine, 5-fluoro-2-iodo-; 5-Fluoro-2-iodoaniline; 2-Amino-4-fluoroiodobenzene; 4-Fluoro-2-iodoaniline
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Iodoaniline is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity (by HPLC), identity confirmation, and impurity profiles. Our quality management system is designed to meet the stringent requirements of our global customer base in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.