Description

3-(Perfluorobutylsulfonyl)-2H-Chromen-2-One is a high-value, fluorinated organic intermediate characterized by its unique perfluoroalkylsulfonyl chromenone structure. This compound is critical for introducing lipophilicity, stability, and specific electronic properties into advanced materials and active pharmaceutical ingredients. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical sectors for synthesizing novel compounds with enhanced performance characteristics.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting enzymes or receptors where fluorination modulates bioavailability and metabolic stability.
• Agrochemical Research: Used in developing next-generation herbicides, fungicides, and insecticides, where the fluorinated moiety can improve environmental persistence and target specificity.
• Material Science: Serves as a precursor for functional polymers, liquid crystals, and organic electronic materials requiring specific fluorinated components for desired optical or electrical properties.
• Organic Synthesis Reagent: Acts as a versatile reagent in advanced organic synthesis, including cyclization reactions and as a source of the perfluorobutylsulfonyl functional group.
• Fluorinated Surfactant & Coating Precursor: Employed in the development of high-performance, oil- and water-repellent surface treatments and specialty surfactants.

Basic Information

Product Name	3-(Perfluorobutylsulfonyl)-2H-Chromen-2-One
CAS No.	254105-73-2
Molecular Formula	C₁₃H₅F₉O₄S
Molecular Weight	476.22 g/mol
Synonyms	3-(Nonafluorobutanesulfonyl)-2H-chromen-2-one; 3-(Perfluorobutanesulfonyl)coumarin; 2H-1-Benzopyran-2-one, 3-[(1,1,2,2,3,3,4,4,4-nonafluorobutyl)sulfonyl]-; 3-(Perfluorobutylsulfonyl)coumarin; 254105-73-2; 3-(Nonafluorobutylsulfonyl)coumarin; PFBS-Coumarin
EINECS	Contact for details

Quality Control

Our production of 3-(Perfluorobutylsulfonyl)-2H-Chromen-2-One adheres to stringent quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.