Description

Ethyl 2-Chloro-4-Methoxypyrimidine-5-Carboxylate is a high-purity, versatile pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its functionalized structure, which allows for selective downstream modifications essential for creating complex molecules. This intermediate is primarily needed by research and development teams and process chemists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral, anticancer, and kinase inhibitor drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential use in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	Ethyl 2-Chloro-4-Methoxypyrimidine-5-Carboxylate
CAS No.	253687-16-0
Molecular Formula	C8H9ClN2O3
Molecular Weight	216.62 g/mol
Synonyms	2-Chloro-4-methoxypyrimidine-5-carboxylic acid ethyl ester; Ethyl 2-chloro-4-methoxy-5-pyrimidinecarboxylate; 5-Pyrimidinecarboxylic acid, 2-chloro-4-methoxy-, ethyl ester; 2-Chloro-4-methoxy-5-(ethoxycarbonyl)pyrimidine; 253687-16-0; Ethyl 2-chloro-4-methoxypyrimidine-5-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Chloro-4-Methoxypyrimidine-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent lot-to-lot performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.