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Methanimidamide, n-6-2-(Dimethylamino)Ethenyl-1,4-Dihydro-5-Nitro-4-Oxo-2-Pyrimidinyl-N,n-Dimethyl- CAS NO 252932-47-1


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CAS No.:252932-47-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Methanimidamide, n-6-2-(Dimethylamino)Ethenyl-1,4-Dihydro-5-Nitro-4-Oxo-2-Pyrimidinyl-N,n-Dimethyl- is a specialized, high-purity chemical intermediate with a complex heterocyclic structure. Its primary value lies in its role as a critical building block for advanced pharmaceutical research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). This compound is essential for R&D chemists and process development scientists working in pharmaceutical, agrochemical, and fine chemical sectors who require reliable, high-quality intermediates for complex synthetic pathways.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocyclic APIs, particularly those targeting specific enzyme inhibition.
  • Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its nitro and pyrimidinyl functional groups.
  • Chemical Biology & Medicinal Chemistry: Serves as a valuable scaffold for constructing molecular libraries in drug discovery and lead optimization programs.
  • Fine Chemical Synthesis: Employed in multi-step organic syntheses to introduce specific functionalized pyrimidine cores into target molecules.
  • Academic & Institutional Research: Used in universities and research institutes for studying reaction mechanisms and developing new synthetic methodologies.

Basic Information

Product Name Methanimidamide, n-6-2-(Dimethylamino)Ethenyl-1,4-Dihydro-5-Nitro-4-Oxo-2-Pyrimidinyl-N,n-Dimethyl-
CAS No. 252932-47-1
Molecular Formula C11H16N6O3
Molecular Weight 280.29 g/mol
Synonyms N,N-Dimethyl-2-[(E)-2-(dimethylamino)ethenyl]-5-nitro-4-oxo-1,4-dihydropyrimidine-6-carboximidamide; 6-Carboximidamide-2-[(E)-2-(dimethylamino)vinyl]-5-nitro-4(1H)-pyrimidinone, N,N-dimethyl-; 2-[(E)-2-(Dimethylamino)vinyl]-5-nitro-4-oxo-1,4-dihydro-6-pyrimidinecarboximidamide, N,N-dimethyl-; (E)-N,N-Dimethyl-2-(2-(dimethylamino)vinyl)-5-nitro-4-oxo-1,4-dihydropyrimidine-6-carboximidamide; 252932-47-1; A potential intermediate for kinase inhibitors.
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Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency for research and development applications. While typically supplied in research or technical grade, specifications can be tailored to meet project-specific purity requirements, including HPLC purity >95% or higher. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after the original container has been opened. Keep away from heat, sparks, and open flame.

Specification

Item Specification
Appearance Yellow to orange crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Loss on Drying ≤ 1.0%
Residue on Ignition ≤ 0.5%
Single Unknown Impurity (HPLC) ≤ 1.0%
Total Impurities (HPLC) ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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