Description

Phenol, 3-(Aminomethyl)-2,6-Difluoro- (9Ci) is a fluorinated phenol derivative featuring an aminomethyl functional group, making it a versatile and valuable bifunctional building block in advanced organic synthesis. This compound is particularly significant for its role in the development of complex molecules, especially within the pharmaceutical and agrochemical sectors, where its unique structure enables precise molecular modifications. It is primarily sought by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), specialty agrochemicals, and high-performance material precursors.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex heterocycles and active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of monomers for specialty polymers, resins, and advanced materials with tailored thermal or chemical resistance.
• Fluorine Chemistry Building Block: Essential for introducing fluorine and phenol functionalities into target molecules in medicinal and synthetic chemistry programs.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific molecule development and scale-up projects.

Basic Information

Product Name	Phenol, 3-(Aminomethyl)-2,6-Difluoro- (9Ci)
CAS No.	252664-91-8
Molecular Formula	C7H7F2NO
Molecular Weight	159.13 g/mol
Synonyms	2,6-Difluoro-3-(aminomethyl)phenol; 3-(Aminomethyl)-2,6-difluorophenol; (3-Aminomethyl-2,6-difluoro)phenol; 2,6-Difluoro-3-hydroxybenzylamine; 3-Hydroxy-2,6-difluorobenzylamine; Benzylamine, 3-hydroxy-2,6-difluoro-; 252664-91-8 (CAS)
EINECS	Contact for details

Quality Control

Our Phenol, 3-(Aminomethyl)-2,6-Difluoro- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality system supports compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.