Description

Phenol, 4-(Aminomethyl)-2,6-Difluoro- (9Ci) is a specialized fluorinated phenol derivative featuring an aminomethyl functional group, making it a versatile and valuable building block in advanced organic synthesis. This compound is particularly significant for its role in creating complex molecules where precise fluorine substitution and amine reactivity are required. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as by manufacturers of specialty materials and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring fluorinated aromatic systems and amine handles for further derivatization.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the difluorophenol moiety can enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalysis, including those for cross-coupling reactions common in fine chemical manufacturing.
• Material Science Research: Employed in the development of novel polymers, resins, and advanced materials where fluorinated aromatic units can impart desirable properties like thermal stability or low surface energy.
• Fluorescent Probe and Dye Chemistry: Acts as a scaffold for synthesizing fluorophores and molecular probes used in biochemical assays and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CMOs for use in custom synthesis projects and scale-up processes for client-specific molecules.

Basic Information

Product Name	Phenol, 4-(Aminomethyl)-2,6-Difluoro- (9Ci)
CAS No.	252664-89-4
Molecular Formula	C7H7F2NO
Molecular Weight	159.13 g/mol
Synonyms	2,6-Difluoro-4-(aminomethyl)phenol; 4-(Aminomethyl)-2,6-difluorophenol; (2,6-Difluoro-4-hydroxyphenyl)methanamine; 2,6-Difluoro-4-hydroxybenzylamine; 4-Hydroxy-3,5-difluorobenzylamine; α-Amino-2,6-difluoro-p-cresol; Benzylamine, 2,6-difluoro-4-hydroxy-
EINECS	Contact for details

Quality Control

Every batch of Phenol, 4-(Aminomethyl)-2,6-Difluoro- (9Ci) undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality management system is designed to meet the stringent requirements of research and industrial-scale applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area%)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.