Description

3-Fluoro-4-(Methylsulfonyl)Aniline is a high-value aromatic amine derivative characterized by its unique fluorine and methylsulfonyl substituents. This compound serves as a critical building block in advanced organic synthesis, offering chemists a versatile handle for constructing complex molecules with tailored electronic and steric properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in kinase inhibitor and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Research: Employed in the creation of specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing sulfonyl group.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing complex, high-performance colorants.
• Cross-Coupling Reactions: The aniline functionality makes it a suitable substrate for Buchwald-Hartwig amination and other palladium-catalyzed transformations.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies for use in bespoke synthesis projects and scale-up processes.

Basic Information

Product Name	3-Fluoro-4-(Methylsulfonyl)Aniline
CAS No.	252561-34-5
Molecular Formula	C7H8FNO2S
Molecular Weight	189.21 g/mol
Synonyms	4-Amino-2-fluoro-1-(methylsulfonyl)benzene; 2-Fluoro-4-aminophenyl methyl sulfone; 3-Fluoro-4-(methylsulfonyl)benzenamine; 4-(Methylsulfonyl)-3-fluoroaniline; Benzenamine, 3-fluoro-4-(methylsulfonyl)-; 3-Fluoro-4-methanesulfonylaniline
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-4-(Methylsulfonyl)Aniline is manufactured and tested under a strict quality management system. We ensure high purity and batch-to-batch consistency through comprehensive analytical techniques including HPLC, GC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.