Description

Fmoc-Ala-Ser(Yme,Mepro)-Oh CAS NO 252554-78-2 is a specialized, orthogonally protected dipeptide building block designed for advanced solid-phase peptide synthesis (SPPS). This compound is critical for researchers and manufacturers requiring precise control over side-chain reactivity and sequential deprotection strategies in complex peptide assembly. It is primarily utilized by the pharmaceutical, biotechnology, and academic research sectors for the development of novel therapeutic peptides, peptidomimetics, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled, sequential assembly of complex peptide sequences, particularly those requiring orthogonal protection for serine and other functional groups.
• Pharmaceutical R&D: Used in the research and development of novel peptide-based drugs, including hormone analogs, antimicrobial peptides, and targeted therapeutics.
• Peptidomimetic Design: Serves as a building block for creating modified peptide structures with enhanced stability, bioavailability, or receptor affinity.
• Combinatorial Chemistry Libraries: Employed in the generation of diverse peptide libraries for high-throughput screening against biological targets.
• Bioconjugation: Can be used in the synthesis of peptide segments intended for conjugation to proteins, antibodies, or other biomolecules.
• Academic & Institutional Research: A valuable reagent for studies in organic chemistry, biochemistry, and medicinal chemistry focused on peptide structure and function.

Basic Information

Product Name	Fmoc-Ala-Ser(Yme,Mepro)-Oh
CAS No.	252554-78-2
Molecular Formula	C27H32N2O7
Molecular Weight	496.56 g/mol
Synonyms	Fmoc-Ala-Ser(Me, Mpro)-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanyl-O-methyl-L-seryl-N-methyl-L-proline; Fmoc-Ala-Ser(OMe)-Mpro-OH; Fmoc-Ala-Ser(Me)-Mpro-OH; Fmoc-L-Ala-L-Ser(OMe)-N-Me-L-Pro-OH; Fmoc-Ala-Ser(OMe, Mepro)-OH; Orthogonally Protected Fmoc-Ala-Ser Dipeptide
EINECS	Contact for details

Quality Control

Our Fmoc-Ala-Ser(Yme,Mepro)-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis to ensure enantiomeric integrity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee reproducible performance in your sensitive synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay (Titration)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.