Description

D-Alanine, n-[(2R)-2-Aminopropyl]- (9Ci) CAS NO 252367-79-6 is a chiral, non-proteinogenic amino acid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a crucial chiral building block and intermediate for the development of novel active pharmaceutical ingredients (APIs), particularly in the creation of peptidomimetics and other bioactive molecules. Its defined stereochemistry and functional groups make it essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors seeking to develop enantiomerically pure products.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, including enzyme inhibitors and receptor modulators.
• Peptidomimetic Synthesis: Used as a building block to create stable peptide analogs with enhanced metabolic stability and bioavailability.
• Agrochemical Research: Serves as an intermediate in the synthesis of chiral herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands for asymmetric catalysis and metal complexes.
• Biochemical Research: Utilized in studies of enzyme mechanisms, metabolic pathways, and as a substrate analog.
• Fine Chemical Synthesis: A versatile intermediate for producing specialty chemicals with specific stereochemical requirements.

Basic Information

Product Name	D-Alanine, n-[(2R)-2-Aminopropyl]- (9Ci)
CAS No.	252367-79-6
Molecular Formula	C6H14N2O2
Molecular Weight	146.19 g/mol
Synonyms	N-[(2R)-2-Aminopropyl]-D-alanine; (R)-N-(2-Aminopropyl)alanine; D-Alanine, N-[(2R)-2-aminopropyl]-; (2R)-2-Aminopropyl-D-alanine; (R)-2-(2-Aminopropylamino)propanoic acid; 252367-79-6; (R)-N-(1-Aminopropan-2-yl)alanine
EINECS	Contact for details

Quality Control

Our production of D-Alanine, n-[(2R)-2-Aminopropyl]- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis to confirm identity, enantiomeric excess, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, and we support compliance with relevant regulatory frameworks for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect stability and purity. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.