Description

Fmoc-D-Cys(Bzl)-Oh CAS NO 252049-18-6 is a protected, non-natural amino acid derivative specifically engineered for solid-phase peptide synthesis (SPPS). This high-purity building block is critical for researchers and manufacturers requiring precise stereochemical control and side-chain protection during the assembly of complex peptides. It is primarily utilized in the pharmaceutical, biotechnology, and academic research sectors for the development of therapeutic peptides, peptidomimetics, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key Fmoc-protected building block for the sequential assembly of custom peptide sequences.
• Therapeutic Peptide Development: Used in the research and production of peptide-based pharmaceuticals, including hormone analogs and antimicrobial peptides.
• Peptidomimetic Design: Incorporation into non-natural peptide structures to enhance stability, bioavailability, and target specificity.
• Bioconjugation and Labeling: The protected thiol group (Cys(Bzl)) allows for specific post-synthetic modifications and attachment of labels or linkers.
• Combinatorial Chemistry Libraries: Serves as a valuable component in high-throughput screening libraries for drug discovery.
• Academic and Industrial Research: Essential reagent for biochemical studies, structure-activity relationship (SAR) analysis, and proteomics research.

Basic Information

Product Name	Fmoc-D-Cys(Bzl)-Oh
CAS No.	252049-18-6
Molecular Formula	C26H23NO4S
Molecular Weight	445.53 g/mol
Synonyms	Fmoc-D-Cys(Bzl)-OH; Fmoc-D-Cysteine(Bzl)-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-S-benzyl-D-cysteine; Fmoc-D-Cys(Bzl); (R)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(benzylthio)propanoic acid; Fmoc-D-Cysteine(S-benzyl)-OH; Fmoc-D-Cys(Bzl)-OH CAS 252049-18-6; D-Fmoc-Cysteine(S-benzyl)
EINECS	Contact for details

Quality Control

Our Fmoc-D-Cys(Bzl)-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive applications like peptide synthesis. Each lot undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm enantiomeric excess. Certificates of Analysis (COA) detailing identity, purity, and specific impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment to maintain stability and prevent degradation. For long-term storage, consider storage at 2-8°C under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (D-isomer)
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.