Description

Fmoc-Orn(Dnp)-Oh is a specialized, orthogonally protected amino acid derivative essential for advanced peptide synthesis. This compound matters for its critical role in enabling the synthesis of complex peptides and peptidomimetics with high precision and minimal side reactions. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in developing therapeutic peptides, diagnostic tools, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key building block for the controlled, sequential assembly of peptides, particularly where selective deprotection of specific functional groups is required.
• Solution-Phase Peptide Synthesis: Used in the synthesis of challenging peptide sequences and cyclic peptides in solution.
• Peptidomimetic Research: Serves as a precursor for creating non-natural amino acid analogs and peptide-like molecules with enhanced stability or biological activity.
• Bioconjugation and Labeling: The orthogonal protecting groups (Fmoc and Dnp) allow for the selective modification of peptides for labeling with fluorophores, biotin, or other functional moieties.
• Pharmaceutical Intermediate: An important intermediate in the research and development stages of novel peptide-based therapeutics.
• Combinatorial Chemistry Libraries: Used to generate diverse libraries of peptide compounds for high-throughput screening in drug discovery.

Basic Information

Product Name	Fmoc-Orn(Dnp)-Oh
CAS No.	252049-04-0
Molecular Formula	C26H24N4O7
Molecular Weight	504.49 g/mol
Synonyms	Fmoc-Orn(Dnp)-OH; N-α-Fmoc-N-δ-Dnp-L-ornithine; Fmoc-L-ornithine(Dnp)-OH; N-δ-(2,4-Dinitrophenyl)-N-α-(9-fluorenylmethoxycarbonyl)-L-ornithine; (2S)-5-[(2,4-Dinitrophenyl)amino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)pentanoic acid; Fmoc-Orn(Dnp)-OH CAS 252049-04-0; Fmoc-Orn(Dnp)
EINECS	Contact for details

Quality Control

Our Fmoc-Orn(Dnp)-Oh is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive research and production applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing specific test results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.