Description

4-Chloro-2,3,6-Trifluorobenzyl Alcohol is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its value lies in the strategic placement of chlorine and fluorine substituents, which allow for selective functionalization and the introduction of unique physicochemical properties into target molecules. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic cores for enhanced metabolic stability, bioavailability, and membrane permeability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms contribute to improved efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in advanced display technologies.
• Polymer Modification: Incorporated into specialty polymers to impart specific properties such as chemical resistance, thermal stability, or altered surface characteristics.
• Organic Electronic Materials: Utilized in the research and development of materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to construct complex biaryl systems.

Basic Information

Product Name	4-Chloro-2,3,6-Trifluorobenzyl Alcohol
CAS No.	252004-68-5
Molecular Formula	C7H3ClF3O
Molecular Weight	198.55 g/mol
Synonyms	(4-Chloro-2,3,6-trifluorophenyl)methanol; 2,3,6-Trifluoro-4-chlorobenzyl Alcohol; α-Hydroxymethyl-4-chloro-2,3,6-trifluorotoluene; 4-Chloro-2,3,6-trifluorobenzenemethanol; Benzyl alcohol, 4-chloro-2,3,6-trifluoro-
EINECS	Contact for details

Quality Control

Our 4-Chloro-2,3,6-Trifluorobenzyl Alcohol is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency meet the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥97% by HPLC), impurity profile, and physical data is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.