Description

4-Bromo-2,3,6-Trifluorobenzyl Alcohol is a high-value, multi-functional fluorinated aromatic building block essential for advanced organic synthesis. This compound matters because its unique combination of bromine and fluorine substituents on a benzyl alcohol scaffold provides versatile reactivity for constructing complex molecules with tailored properties. It is primarily needed by R&D chemists and process engineers in the pharmaceutical and agrochemical industries for developing new active ingredients, as well as in materials science for creating specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorine-containing drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity, metabolic stability, and membrane permeability.
• Liquid Crystal Materials: Serves as a crucial precursor for fluorine-based liquid crystal molecules used in high-performance displays (LCDs).
• Polymer & Material Science: Employed to introduce fluorinated aromatic units into polymers, improving chemical resistance, thermal stability, and optical properties.
• Cross-Coupling Reactions: The bromine atom acts as an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck), enabling rapid diversification of molecular structures.
• Organic Synthesis Building Block: The benzyl alcohol group can be readily oxidized to aldehydes or carboxylic acids, or used in etherification/esterification reactions, making it a versatile starting point for complex molecule assembly.

Basic Information

Product Name	4-Bromo-2,3,6-Trifluorobenzyl Alcohol
CAS No.	252004-34-5
Molecular Formula	C7H3BrF3O
Molecular Weight	236.99 g/mol
Synonyms	(4-Bromo-2,3,6-trifluorophenyl)methanol; 2,3,6-Trifluoro-4-bromobenzyl Alcohol; α-Hydroxymethyl-4-bromo-2,3,6-trifluorotoluene; 4-Bromo-2,3,6-trifluorobenzylalcohol; 4-Bromo-α,2,3-trifluorobenzyl Alcohol; (4-Bromo-2,3,6-trifluoromethyl)methanol; 4-Bromo-2,3,6-trifluoro-benzenemethanol
EINECS	Contact for details

Quality Control

Our 4-Bromo-2,3,6-Trifluorobenzyl Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and scale-up applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability, consistency, and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.