Description

5-Fluoro-2-(1H-Imidazol-1-Yl)Aniline is a high-purity, multi-functional heterocyclic aromatic amine building block, essential for advanced organic synthesis. Its core value lies in its unique molecular architecture, combining an aniline moiety with an imidazole ring and a fluorine substituent, which is critical for modulating the biological activity and physicochemical properties of target molecules. This compound is primarily required by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors, antifungal agents, and other biologically active heterocycles.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, where the fluorine atom and imidazole ring contribute to enhanced efficacy and environmental stability.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers, dyes, and advanced organic electronic materials.
• Chemical Biology & Proteomics: Employed as a versatile scaffold or labeling reagent in the design of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for bespoke synthesis projects requiring high-fidelity, complex aromatic amines.

Basic Information

Product Name	5-Fluoro-2-(1H-Imidazol-1-Yl)Aniline
CAS No.	251649-52-2
Molecular Formula	C9H8FN3
Molecular Weight	177.18 g/mol
Synonyms	1-(2-Amino-4-fluorophenyl)-1H-imidazole; 2-Amino-4-fluoro-1-(1H-imidazol-1-yl)benzene; 4-Fluoro-2-(1H-imidazol-1-yl)aniline; 5-Fluoro-2-(imidazol-1-yl)aniline; 2-(1H-Imidazol-1-yl)-5-fluoroaniline; 5-Fluoro-2-(1H-imidazol-1-yl)benzenamine; 251649-52-2
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-(1H-Imidazol-1-Yl)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.