Description

Dynamin Inhibitory Peptide is a synthetic, cell-permeable peptide designed to specifically inhibit the GTPase activity of dynamin, a key protein involved in clathrin-mediated endocytosis. This targeted inhibition makes it a critical research tool for studying intracellular trafficking, synaptic vesicle recycling, and receptor internalization pathways. It is essential for researchers in neuroscience, cell biology, and pharmacology who require precise molecular tools to dissect endocytic mechanisms and their implications in disease.

Application

• Neuroscience Research: Investigation of synaptic vesicle endocytosis and neurotransmitter release dynamics.
• Cell Signaling Studies: Elucidation of growth factor and G-protein coupled receptor (GPCR) internalization and downstream signaling pathways.
• Viral Entry Research: Study of clathrin-dependent viral entry mechanisms for various pathogens.
• Drug Discovery: Target validation and screening in programs focused on endocytosis-related disorders.
• Basic Cell Biology: Fundamental research on clathrin-mediated endocytosis, membrane trafficking, and cytoskeletal dynamics.
• Biochemical Assays: Used as a control or active agent in in vitro GTPase activity assays.

Basic Information

Product Name	Dynamin Inhibitory Peptide
CAS No.	251634-21-6
Molecular Formula	C95H147N29O26S
Molecular Weight	2155.4 g/mol
Synonyms	Dynamin Inhibitory Peptide; Dynasore Peptide Analog; Myristoylated Dynamin Inhibitory Peptide; Myr-Dynamin Inhibitory Peptide; Myr-4-PIQVPSRPNRAPP; Peptide Inhibitor of Dynamin; PID; Dynamin GTPase Inhibitory Peptide
EINECS	Contact for details

Quality Control

Our Dynamin Inhibitory Peptide is manufactured under stringent conditions to ensure the highest standards of purity and biological activity. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, sequence verification, and mass spectrometry data. We adhere to ISO 9001 quality management principles, and our processes are designed to meet the exacting requirements of life science research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, solutions should be prepared in appropriate buffers, aliquoted, and stored at -80°C to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Peptide Content	≥ 70%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO, or aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.