Description

5-Bromo-3-Fluorosalicylaldehyde is a halogenated salicylaldehyde derivative, a versatile and high-value organic building block. This compound is prized for its unique molecular structure, which combines an aldehyde group with bromine and fluorine substituents on an aromatic ring, enabling precise chemical modifications. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing novel active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where the bromo and fluoro groups enhance biological activity and stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the preparation of functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Useful for designing fluorescent probes and molecular tags for biochemical and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	5-Bromo-3-Fluorosalicylaldehyde
CAS No.	251300-28-4
Molecular Formula	C7H4BrFO2
Molecular Weight	219.01 g/mol
Synonyms	3-Fluoro-5-bromosalicylaldehyde; 2-Hydroxy-5-bromo-3-fluorobenzaldehyde; 5-Bromo-3-fluoro-2-hydroxybenzaldehyde; Salicylaldehyde, 5-bromo-3-fluoro-; Benzaldehyde, 2-hydroxy-5-bromo-3-fluoro-; 5-Bromo-3-fluorosalicylic aldehyde
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Fluorosalicylaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with all shipments, detailing batch-specific results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.