Description

2-(9H-Fluoren-9-Ylmethoxycarbonylamino)-3-(4-Nitro-Phenyl)-Propionic Acid is a specialized Fmoc-protected amino acid derivative, a key building block in solid-phase peptide synthesis (SPPS). Its core value lies in enabling the precise and efficient construction of complex peptide sequences, particularly those incorporating modified tyrosine analogs. This high-purity intermediate is essential for research and development laboratories in the pharmaceutical and biotechnology sectors, where it is used to synthesize novel therapeutic peptides, peptide mimetics, and for advanced biochemical research.

Application

• Solid-Phase Peptide Synthesis (SPPS): A critical protected amino acid building block for the automated synthesis of custom peptides.
• Pharmaceutical R&D: Used in the research and development of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Bioconjugation: Serves as a precursor for creating peptide-protein or peptide-small molecule conjugates for targeted therapies.
• Chemical Biology Probes: Employed in the synthesis of labeled or modified peptides used as tools to study biological processes and protein interactions.
• Combinatorial Chemistry: A valuable component in libraries for high-throughput screening to discover new bioactive compounds.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic chemistry, medicinal chemistry, and biochemistry.

Basic Information

Product Name	2-(9H-Fluoren-9-Ylmethoxycarbonylamino)-3-(4-Nitro-Phenyl)-Propionic Acid
CAS No.	250740-52-4
Molecular Formula	C24H20N2O6
Molecular Weight	432.43 g/mol
Synonyms	Fmoc-4-Nitro-Phenylalanine; Fmoc-Phe(4-NO2)-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-4-nitrophenylalanine; 2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(4-nitrophenyl)propanoic acid; Fmoc-4-Nitrophenylalanine-OH; N-Fmoc-4-nitrophenylalanine; (2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-nitrophenyl)propanoic acid (for L-isomer)
EINECS	Contact for details

Quality Control

Our 2-(9H-Fluoren-9-Ylmethoxycarbonylamino)-3-(4-Nitro-Phenyl)-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive peptide synthesis applications. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.