Description

o-Acetyl-L-Homoserine Hydrochloride is a protected derivative of the non-proteinogenic amino acid L-homoserine, serving as a crucial chiral building block in advanced organic synthesis. This compound matters for its role in the efficient production of complex molecules, offering a reactive handle for further chemical elaboration while preserving stereochemical integrity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, peptide mimetics, and biochemical research tools.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly those targeting metabolic pathways.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis to incorporate modified homoserine residues into peptide chains.
• Biochemical Research: Serves as a precursor or standard in enzymatic studies and metabolic pathway analysis.
• Agrochemical Development: Employed in the research and synthesis of advanced, biologically active compounds for crop protection.
• Asymmetric Synthesis: Utilized as a starting material for the construction of complex, enantiomerically pure natural product analogs.

Basic Information

Product Name	o-Acetyl-L-Homoserine Hydrochloride
CAS No.	250736-84-6
Molecular Formula	C7H13NO5 • HCl
Molecular Weight	227.64 g/mol
Synonyms	O-Acetyl-L-homoserine HCl; L-Homoserine, O-acetate, hydrochloride; (2S)-2-Amino-4-(acetyloxy)butanoic acid hydrochloride; Acetyl-L-homoserine hydrochloride; N-Acetyl-L-homoserine hydrochloride (common misnomer); 2-Acetoxy-4-aminobutanoic acid hydrochloride; L-2-Amino-4-acetoxybutyric acid hydrochloride
EINECS	Contact for details

Quality Control

Our o-Acetyl-L-Homoserine Hydrochloride is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling by HPLC, to ensure it meets high-purity standards suitable for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific tests is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. The container should be sealed immediately after use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.