Description

Pyrimidine, 2-[(Fluoromethyl)Thio]- (9Ci) is a specialized fluorinated and sulfur-containing heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, which combines a pyrimidine core with a reactive fluoromethylthio moiety, enabling precise modifications in target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients, particularly where the introduction of fluorine and sulfur is desired for tuning biological activity, metabolic stability, or physicochemical properties.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, especially for antiviral, anticancer, and antimicrobial agents.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the fluoromethylthio group can enhance efficacy and environmental profile.
• Material Science Research: Investigated as a precursor for functionalized materials, such as ligands for catalysis or monomers for specialty polymers.
• Chemical Biology Probes: Utilized in the design of molecular probes and labeling reagents due to the reactivity of the thioether and fluorine groups.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic and organofluorine chemistry.

Basic Information

Product Name	Pyrimidine, 2-[(Fluoromethyl)Thio]- (9Ci)
CAS No.	250690-55-2
Molecular Formula	C5H5FN2S
Molecular Weight	144.17 g/mol
Synonyms	2-[(Fluoromethyl)thio]pyrimidine; 2-(Fluoromethylsulfanyl)pyrimidine; (Fluoromethyl)(pyrimidin-2-yl)sulfane; 2-Pyrimidinyl fluoromethyl sulfide; 250690-55-2; SCHEMBL21842279; DTXSID70731892
EINECS	Contact for details

Quality Control

Our production of Pyrimidine, 2-[(Fluoromethyl)Thio]- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and sensitive to strong alkali/organic solvent. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.