Description

2,4(1H,3H)-Pyrimidinedione, 5-Ethynyl-1-Methyl- (9Ci) is a specialized pyrimidine derivative, a key heterocyclic scaffold in medicinal chemistry and advanced material science. This compound matters for its role as a versatile synthetic intermediate, enabling the construction of complex molecules through its reactive ethynyl group. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of nucleoside analogs, antiviral agents, and novel polymers.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel nucleoside and nucleotide analogs for antiviral and anticancer research.
• Organic Synthesis Reagent: Utilized in click chemistry and Sonogashira coupling reactions due to its reactive ethynyl functionality for constructing complex molecular architectures.
• Biochemical Research: Used in the study of enzyme inhibitors and as a probe or precursor in the development of diagnostic agents.
• Material Science: Acts as a monomer or precursor for the development of specialty polymers and advanced organic electronic materials.
• Agrochemical Research: Investigated as an intermediate in the development of new active ingredients for crop protection.

Basic Information

Product Name	2,4(1H,3H)-Pyrimidinedione, 5-Ethynyl-1-Methyl- (9Ci)
CAS No.	250658-12-9
Molecular Formula	C7H6N2O2
Molecular Weight	150.14 g/mol
Synonyms	5-Ethynyl-1-methyluracil; 1-Methyl-5-ethynyluracil; 5-Ethynyl-1-methyl-2,4(1H,3H)-pyrimidinedione; 5-Ethynyl-1-methylpyrimidine-2,4(1H,3H)-dione; 1-Methyl-5-ethynyl-2,4-dihydroxypyrimidine; 5-Ethynyl-1-methyl-dihydroxypyrimidine
EINECS	Contact for details

Quality Control

Our 2,4(1H,3H)-Pyrimidinedione, 5-Ethynyl-1-Methyl- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.