Description

Fmoc-Trp-His-Trp-Leu-Gln-Leu-Lys-Pro-Gly-Gln-Pro-Met-Tyr-Oh is a synthetic peptide sequence containing multiple tryptophan (Trp) and other amino acid residues, protected with a fluorenylmethyloxycarbonyl (Fmoc) group at the N-terminus. This compound is critical for advanced peptide synthesis and research, particularly in the development of novel bioactive molecules and pharmaceutical intermediates. It is primarily utilized by research institutions, biotechnology companies, and pharmaceutical developers focused on peptide-based drug discovery, structure-activity relationship (SAR) studies, and biochemical assays.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or a model compound in the synthesis of complex peptide-based therapeutics and novel drug candidates.
• Peptide Synthesis (SPPS): Used as a building block in solid-phase peptide synthesis (SPPS) protocols, especially where the Fmoc protecting group strategy is employed.
• Biochemical & Biophysical Studies: Employed in research to study peptide-protein interactions, membrane permeability, and the structural properties of specific amino acid sequences.
• Antimicrobial Peptide (AMP) Research: The tryptophan-rich sequence suggests potential utility in the design and screening of novel antimicrobial peptides.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting fundamental research in biochemistry, medicinal chemistry, and molecular biology.
• Reference Standard: Can be used as a high-purity reference standard for analytical method development and quality control in peptide manufacturing.

Basic Information

Product Name	Fmoc-Trp-His-Trp-Leu-Gln-Leu-Lys-Pro-Gly-Gln-Pro-Met-Tyr-Oh
CAS No.	250642-63-8
Molecular Formula	C99H128N22O20S
Molecular Weight	2002.3 g/mol
Synonyms	Fmoc-WHWQLQKPGQPMY-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-tryptophyl-L-histidyl-L-tryptophyl-L-leucyl-L-glutaminyl-L-leucyl-L-lysyl-L-prolylglycyl-L-glutaminyl-L-prolyl-L-methionyl-L-tyrosine; Fmoc-Trp-His-Trp-Leu-Gln-Leu-Lys-Pro-Gly-Gln-Pro-Met-Tyr; Fmoc protected peptide; Peptide synthesis intermediate; Fmoc-WHWQLQKPGQPMY
EINECS	Contact for details

Quality Control

Our peptide products are manufactured under strict quality management systems. Each batch of Fmoc-Trp-His-Trp-Leu-Gln-Leu-Lys-Pro-Gly-Gln-Pro-Met-Tyr-Oh undergoes rigorous analytical testing, including HPLC for purity and MS for identity confirmation, to ensure compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC-MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Analysis	Within ± 10% of theoretical
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.