Description

Boc-Lys(Fmoc)-Leu-Ala-Leu-Oh is a protected tetrapeptide building block of significant interest in pharmaceutical research and development. This compound is specifically designed for use in solid-phase peptide synthesis (SPPS), where its orthogonal protecting groups allow for precise, sequential chain elongation. It is an essential intermediate for researchers and manufacturers developing novel peptide-based therapeutics, diagnostics, and biochemical tools. The product is supplied as a high-purity material to ensure optimal coupling efficiency and final product quality.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected intermediate for the controlled assembly of complex peptide sequences in automated synthesizers.
• Pharmaceutical R&D: Used in the discovery and development of new peptide drugs targeting various diseases.
• Bioconjugation: Serves as a precursor for creating peptide-protein or peptide-small molecule conjugates for targeted therapies.
• Biochemical Research: Employed in structure-activity relationship (SAR) studies to understand the function of specific amino acid sequences.
• Production of Custom Peptides: A critical raw material for CROs and CDMOs manufacturing bespoke peptides for clients.
• Library Synthesis: Used in combinatorial chemistry to generate diverse peptide libraries for high-throughput screening.

Basic Information

Product Name	Boc-Lys(Fmoc)-Leu-Ala-Leu-Oh
CAS No.	250290-84-7
Molecular Formula	C44H64N6O10
Molecular Weight	837.02 g/mol
Synonyms	Boc-Lys(Fmoc)-Leu-Ala-Leu-OH; tert-Butyloxycarbonyl-Nε-fluorenylmethoxycarbonyl-L-lysyl-L-leucyl-L-alanyl-L-leucine; Boc-Lys(Fmoc)-Leu-Ala-Leu; Fmoc-Lys(Boc)-Leu-Ala-Leu-OH; Nα-Boc-Nε-Fmoc-L-lysyl-L-leucyl-L-alanyl-L-leucine; Protected Tetrapeptide Boc-Lys(Fmoc)-Leu-Ala-Leu; (S)-2-((S)-2-((S)-2-((S)-6-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-((tert-butoxycarbonyl)amino)hexanamido)-4-methylpentanamido)propanamido)-4-methylpentanoic acid
EINECS	Contact for details

Quality Control

Our Boc-Lys(Fmoc)-Leu-Ala-Leu-Oh is manufactured under strict quality control protocols to ensure it meets the high-purity standards required for sensitive peptide synthesis. Each batch is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 1.0%
Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.