Description

Boc-Gly-Phe-Gly-Lys-Oh is a protected tetrapeptide derivative, widely utilized as a crucial building block in solid-phase peptide synthesis (SPPS). Its value lies in the orthogonal protection strategy, where the N-terminal tert-butyloxycarbonyl (Boc) group and the C-terminal free acid allow for precise, sequential chain elongation. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing novel peptide-based therapeutics, diagnostics, and biochemical tools. Its defined structure ensures reproducibility and high purity in complex peptide assembly processes.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of longer, biologically active peptide sequences for drug discovery and development.
• Bioconjugation & Probe Synthesis: Used to create peptide tags or ligands for labeling proteins, antibodies, or other biomolecules in diagnostic assays.
• Biochemical Research: Serves as a standard or substrate in enzymatic studies, receptor-ligand interaction assays, and structural biology.
• Antigen Peptide Production: Employed in the custom synthesis of peptide antigens for antibody generation and immunological studies.
• Material Science: Potential use as a component in the design of peptide-based biomaterials and hydrogels.

Basic Information

Product Name	Boc-Gly-Phe-Gly-Lys-Oh
CAS No.	250290-82-5
Molecular Formula	C27H42N6O7
Molecular Weight	562.66 g/mol
Synonyms	Boc-Gly-Phe-Gly-Lys-OH; Boc-Gly-L-Phe-Gly-L-Lys-OH; N-[(1,1-Dimethylethoxy)carbonyl]glycyl-L-phenylalanylglycyl-L-lysine; tert-Butyloxycarbonyl-glycyl-phenylalanyl-glycyl-lysine; Nα-Boc-Gly-Phe-Gly-Lys-OH; Boc-Gly-Phe-Gly-Lys; (2S)-6-Amino-2-[[2-[[2-[(2-[[(2-methylpropan-2-yl)oxycarbonyl]amino]acetyl)amino]-3-phenylpropanoyl]amino]acetyl]amino]hexanoic acid
EINECS	Contact for details

Quality Control

Our Boc-Gly-Phe-Gly-Lys-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided to guarantee compliance with your research or cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.