Description

Boc-Gly-Gly-Gly-Lys-Oh CAS NO 250290-81-4 is a protected tetrapeptide building block, specifically featuring a Boc (tert-butoxycarbonyl) group on the N-terminus and a free carboxylic acid on the C-terminus. This compound is a critical intermediate for the solid-phase and solution-phase synthesis of longer, more complex peptides, enabling precise control over sequence and structure. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in developing novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate in the synthesis of potential peptide-based drug candidates for various therapeutic areas.
• Solid-Phase Peptide Synthesis (SPPS): Used as a protected amino acid segment for the efficient, sequential assembly of custom peptide sequences.
• Bioconjugation & Probe Development: The free carboxyl group allows for conjugation to other molecules, such as fluorophores or carriers, to create labeled peptides for diagnostic or imaging applications.
• Biochemical Research: Employed in studying enzyme-substrate interactions, protein folding, and other structure-activity relationship (SAR) studies.
• Production of Specialty Peptides: A vital raw material for contract manufacturing organizations (CMOs) producing custom peptides at gram to kilogram scale for commercial and clinical use.

Basic Information

Product Name	Boc-Gly-Gly-Gly-Lys-Oh
CAS No.	250290-81-4
Molecular Formula	C19H34N6O7
Molecular Weight	458.51 g/mol
Synonyms	Boc-Gly-Gly-Gly-Lys-OH; N-α-(tert-Butoxycarbonyl)-glycyl-glycyl-glycyl-L-lysine; tert-Butyloxycarbonyl-Gly-Gly-Gly-Lys-OH; Boc-GGGK-OH; (2S)-6-Amino-2-[(2-{2-[(2-{[(tert-butoxy)carbonyl]amino}acetyl)amino]acetyl}amino)acetyl]amino]hexanoic acid; Boc-Gly-Gly-Gly-Lys; GGGK(Boc)
EINECS	Contact for details

Quality Control

Every batch of Boc-Gly-Gly-Gly-Lys-Oh is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity required for sensitive research and production applications. Certificates of Analysis (COA) detailing purity, chiral integrity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.