Description

Boc-Gln-Gln-Oh is a protected dipeptide building block of significant importance in synthetic organic and medicinal chemistry. Its primary value lies in providing a controlled, sequential method for constructing complex peptide chains, particularly those containing glutamine residues, without unwanted side reactions. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors engaged in peptide synthesis, drug discovery, and the development of novel therapeutic agents.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of two consecutive glutamine units into target peptide sequences.
• Solution-Phase Peptide Synthesis: Used in classical coupling strategies for constructing specific peptide fragments in solution.
• Pharmaceutical Research: Serves as a crucial building block in the discovery and development of peptide-based drugs and bioactive compounds.
• Bioconjugation: Can be utilized in the synthesis of peptide tags or linkers for protein labeling and bioconjugation applications.
• Chemical Biology Probes: Employed in the creation of specialized peptides used as tools for studying biological processes and enzyme functions.
• Custom Peptide Service: A fundamental raw material for contract research and manufacturing organizations (CROs/CMOs) offering bespoke peptide synthesis.

Basic Information

Product Name	Boc-Gln-Gln-Oh
CAS No.	250290-76-7
Molecular Formula	C₁₆H₂₈N₄O₇
Molecular Weight	388.42 g/mol
Synonyms	Boc-Gln-Gln-OH; N-α-(tert-Butoxycarbonyl)-L-glutaminyl-L-glutamine; (2S)-2-[[(2S)-5-amino-2-[(2-methylpropan-2-yl)oxycarbonylamino]-5-oxopentanoyl]amino]-5-aminopentanoic acid; Boc-L-Gln-L-Gln-OH; N-Boc-L-glutaminyl-L-glutamine; tert-Butoxycarbonyl-glutaminyl-glutamine; Boc-Gln-Gln; BOC-GLN-GLN-OH
EINECS	Contact for details

Quality Control

Every batch of Boc-Gln-Gln-Oh is manufactured and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Specific Rotation	-20.0° to -24.0° (c=1, DMF)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.