Description

Phenol, 2,3,5,6-Tetrafluoro-, Dihydrate (9Ci) is a fluorinated phenol derivative of significant interest in advanced chemical synthesis and material science. This compound serves as a critical building block for introducing fluorine atoms and phenolic functionality into target molecules, enabling the fine-tuning of electronic properties, lipophilicity, and metabolic stability. It is primarily sought by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries for developing novel active ingredients and high-performance materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutics.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides and pesticides where fluorine substitution enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorine-containing mesogens and electron-transport materials, improving display performance and efficiency.
• Polymer Modification: Incorporated as a monomer or additive to create fluorinated epoxy resins, polycarbonates, and other engineering plastics with enhanced chemical resistance and thermal stability.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and nucleophilic aromatic substitution to construct complex, fluorinated aromatic systems.
• Surface Modification Agent: Used to develop hydrophobic and oleophobic coatings for textiles, electronics, and medical devices.

Basic Information

Product Name	Phenol, 2,3,5,6-Tetrafluoro-, Dihydrate (9Ci)
CAS No.	250261-32-6
Molecular Formula	C6H4F4O · 2H2O
Molecular Weight	188.10 g/mol (anhydrous basis)
Synonyms	2,3,5,6-Tetrafluorophenol Dihydrate; Tetrafluorophenol Dihydrate; 2,3,5,6-Tetrafluoro-1-hydroxybenzene Dihydrate; Perfluorophenol Dihydrate (common name); TFP Dihydrate; 1-Hydroxy-2,3,5,6-tetrafluorobenzene Dihydrate; NSC 406306 Dihydrate
EINECS	Contact for details

Quality Control

Our Phenol, 2,3,5,6-Tetrafluoro-, Dihydrate (9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for water content, to ensure it meets the stringent requirements of research and industrial applications. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The dihydrate form is moisture-sensitive; prolonged exposure to humid air should be avoided to prevent changes in hydration state.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	16.0 - 19.0% (Theoretical for dihydrate: ~19.1%)
Melting Point	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.