Description

Boc-Asn-Phe-Pro-Aldehyde CAS NO 249757-11-7 is a protected tripeptide aldehyde derivative, serving as a key building block and protease inhibitor scaffold in advanced organic synthesis. This compound is valued for its role in the development of enzyme inhibitors and as a crucial intermediate in peptide-based drug discovery. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions focused on medicinal chemistry and proteomics.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel protease inhibitors and other therapeutic peptides.
• Biochemical Research: Used as a selective inhibitor to study the function and mechanism of specific proteolytic enzymes in biological pathways.
• Medicinal Chemistry: Serves as a scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Peptide Synthesis: Employed in solid-phase and solution-phase peptide synthesis to introduce specific aldehyde functionalities.
• Chemical Biology Probes: Utilized in the development of activity-based probes for labeling and profiling enzyme activities in complex samples.

Basic Information

Product Name	Boc-Asn-Phe-Pro-Aldehyde
CAS No.	249757-11-7
Molecular Formula	C₂₄H₃₄N₄O₇
Molecular Weight	490.55 g/mol
Synonyms	Boc-Asparagine-Phenylalanine-Proline Aldehyde; tert-Butyloxycarbonyl-Asn-Phe-Pro-al; Boc-N-F-P-al; (2S)-1-[(2S)-2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-carbamoylbutanoyl]amino]-3-phenylpropanoyl]pyrrolidine-2-carbaldehyde; N-[(tert-Butoxy)carbonyl]-L-asparaginyl-L-phenylalanyl-L-prolinal; Boc-L-Asn-L-Phe-L-Pro-al; Peptide aldehyde inhibitor precursor
EINECS	Contact for details

Quality Control

Our Boc-Asn-Phe-Pro-Aldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis to ensure stereochemical integrity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.