Description

L-Isoleucine, 5-Methoxy- (9Ci) is a modified amino acid derivative, specifically a methoxylated analog of the essential branched-chain amino acid L-Isoleucine. This compound is of significant interest in advanced pharmaceutical research and fine chemical synthesis, serving as a critical chiral building block. It is primarily utilized by researchers and manufacturers in the life sciences sector for developing novel therapeutic agents, peptide-based drugs, and biochemical probes.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for metabolic and neurological disorders.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate modified amino acid residues, altering the stability, activity, or bioavailability of peptide drugs.
• Biochemical Research: Serves as a standard or reagent in metabolic pathway studies, enzyme-substrate interaction research, and proteomics.
• Fine Chemical Production: Employed as a specialized building block for synthesizing complex organic molecules with high stereochemical purity in custom synthesis projects.
• Nutraceutical R&D: Investigated for potential applications in advanced nutritional supplements and specialized clinical nutrition formulations.

Basic Information

Product Name	L-Isoleucine, 5-Methoxy- (9Ci)
CAS No.	245332-22-3
Molecular Formula	C10H21NO3
Molecular Weight	203.28 g/mol
Synonyms	5-Methoxy-L-isoleucine; (2S,3S)-2-Amino-3-methyl-5-methoxypentanoic acid; L-5-Methoxyisoleucine; (2S,3S)-5-Methoxyisoleucine; 5-Methoxyisoleucine; 5-Methoxy-L-isoleucine; 5-Methoxyisoleucine, L-; 5-Methoxyisoleucine (L-isoleucine derivative)
EINECS	Contact for details

Quality Control

Our L-Isoleucine, 5-Methoxy- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling via HPLC, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing specific results for identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.