Description

L-N(W)-Nitroarginine-2 4-Diaminobutryic is a specialized, high-purity biochemical building block and research compound. This modified arginine derivative is critical for advanced biochemical research, particularly in the study of nitric oxide synthase (NOS) inhibition and related cellular signaling pathways. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers developing novel therapeutic agents and biochemical tools.

Application

• Nitric Oxide Synthase (NOS) Research: Serves as a key biochemical tool and reference standard in studies investigating NOS enzyme activity, inhibition mechanisms, and the role of nitric oxide in physiological and pathological processes.
• Pharmaceutical Intermediate: Used in the research and development of potential therapeutic agents targeting cardiovascular diseases, neurological disorders, and inflammatory conditions where NOS modulation is relevant.
• Biochemical Probe Development: Acts as a precursor or core structure for synthesizing labeled compounds (e.g., fluorescent or radioactive probes) for cellular imaging and target engagement studies.
• Enzyme Kinetics & Mechanism Studies: Employed in detailed enzymatic assays to determine kinetic parameters (IC50, Ki) and elucidate the structure-activity relationships (SAR) of NOS inhibitors.
• Academic & Institutional Research: Supports fundamental research in biochemistry, cell biology, and pharmacology within university and government research laboratories.

Basic Information

Product Name	L-N(W)-Nitroarginine-2 4-Diaminobutryic
CAS No.	244185-39-5
Molecular Formula	C10H21N7O4
Molecular Weight	303.32 g/mol
Synonyms	L-Nω-Nitroarginine-2,4-diaminobutyric acid; Nω-Nitro-L-arginine-2,4-diaminobutyric acid; 2,4-Diaminobutyric acid, Nω-nitro-L-arginine-; (2S)-2-Amino-5-[(diaminomethylidene)amino]-2-[(4-nitrooxybutyl)carbamoyl]pentanoic acid; Nω-Nitro-L-arginine Dab conjugate; Nitroarginine-Dab; NOS Inhibitor research compound; Modified arginine derivative
EINECS	Contact for details

Quality Control

Our L-N(W)-Nitroarginine-2 4-Diaminobutryic is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for reliable research outcomes. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support research and development needs with materials suitable for laboratory use, with specifications available to meet project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.