Description

4-Chloro-5,8-Dihydro-6H-Pyrano[4',3':4,5]Thieno[2,3-D]Pyrimidine is a high-value, multi-cyclic heteroaromatic building block of significant interest in advanced organic synthesis. This compound matters because it provides a sophisticated, fused-ring scaffold that is crucial for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. Pharmaceutical and agrochemical research organizations need this intermediate to explore new therapeutic and crop protection agents, leveraging its unique structural features to modulate biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel kinase inhibitors, anticancer agents, and other small-molecule therapeutics.
• Agrochemical Research: Used as a core scaffold for developing new fungicides, herbicides, and insecticides with novel modes of action.
• Chemical Biology Probe: Serves as a starting material for creating molecular probes to study enzyme function and biological pathways.
• Material Science Research: Investigated as a potential building block for organic electronic materials due to its fused heterocyclic structure.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects and library generation.

Basic Information

Product Name	4-Chloro-5,8-Dihydro-6H-Pyrano[4',3':4,5]Thieno[2,3-D]Pyrimidine
CAS No.	243968-08-3
Molecular Formula	C11H9ClN2OS
Molecular Weight	252.72 g/mol
Synonyms	4-Chloro-5,8-dihydro-6H-pyrano[4',3':4,5]thieno[2,3-d]pyrimidine; 4-Chloro-6H-pyrano[4',3':4,5]thieno[2,3-d]pyrimidine, 5,8-dihydro-; 243968-08-3; 4-Chloro-5,8-dihydro-6H-pyrano[4',3':4,5]thieno[2,3-d]pyrimidine; Thieno[2,3-d]pyrimidine, 4-chloro-5,8-dihydro-6H-pyrano[4',3':4,5]-; Pyrano[4',3':4,5]thieno[2,3-d]pyrimidine, 4-chloro-5,8-dihydro-6H-
EINECS	Contact for details

Quality Control

Our 4-Chloro-5,8-Dihydro-6H-Pyrano[4',3':4,5]Thieno[2,3-D]Pyrimidine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect this moisture-sensitive material.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.