Description

Lysine, 5-Fluoro- (9Ci) CAS NO 243671-05-8 is a fluorinated derivative of the essential amino acid L-lysine, where a fluorine atom is introduced at the 5-position of the carbon chain. This specific modification is crucial for creating advanced pharmaceutical intermediates and biochemical probes, offering enhanced metabolic stability and binding affinity in target molecules. It is primarily required by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, diagnostic agents, and in biochemical studies exploring protein function and interaction.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of fluorinated peptide-based drugs and protease inhibitors.
• Biochemical Research: Used as a stable, non-radioactive tracer or probe in metabolic pathway studies and enzyme kinetics.
• Proteomics & Peptide Synthesis: Incorporated into custom peptides to study structure-activity relationships (SAR) and enhance peptide stability against enzymatic degradation.
• Agrochemical Development: Serves as a precursor in the research and development of novel, fluorinated amino acid-based plant growth regulators or herbicides.
• Diagnostic Agent Precursor: Utilized in the creation of contrast agents or ligands for Positron Emission Tomography (PET) imaging when labeled with fluorine-18.
• Material Science: A potential monomer for synthesizing specialized fluorinated polymers with unique surface properties.

Basic Information

Product Name	Lysine, 5-Fluoro- (9Ci)
CAS No.	243671-05-8
Molecular Formula	C6H13FN2O2
Molecular Weight	164.18 g/mol
Synonyms	5-Fluoro-L-lysine; 5-Fluorolysine; (2S)-2,6-Diamino-5-fluorohexanoic acid; 5-Fluoro-DL-lysine; FL; F-Lys; 5-Fluoronorleucine (related); 2,6-Diamino-5-fluorohexanoic acid
EINECS	Contact for details

Quality Control

Our Lysine, 5-Fluoro- (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.