Description

2-Fluoro-5-(Trifluoromethyl)Propiophenone, 97 is a high-purity fluorinated aromatic ketone building block, identified by CAS No. 242812-12-0. This compound is valued for its unique trifluoromethyl and fluorine substituents, which are critical for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules in advanced synthesis. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients. Its role as a key intermediate enables the exploration of new chemical entities with potential therapeutic and crop protection applications.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Material Synthesis: Serves as a precursor for fluorinated aromatic cores used in electronic display materials and organic light-emitting diodes (OLEDs).
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with enhanced chemical resistance, thermal stability, and unique surface properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, catalysis studies, and exploring new fluorination reactions.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses producing complex, fluorinated organic molecules on a commercial scale.

Basic Information

Product Name	2-Fluoro-5-(Trifluoromethyl)Propiophenone, 97
CAS No.	242812-12-0
Molecular Formula	C10H8F4O
Molecular Weight	220.16 g/mol
Synonyms	1-(2-Fluoro-5-(trifluoromethyl)phenyl)propan-1-one; 2-Fluoro-α-ethyl-α-(trifluoromethyl)benzenemethanol (tautomer); 2-Fluoro-5-(trifluoromethyl)propiophenone; Propiophenone, 2-fluoro-5-(trifluoromethyl)-; 2-Fluoro-α-ethyl-α-(trifluoromethyl)benzyl alcohol; 242812-12-0; 2-Fluoro-5-trifluoromethylpropiophenone
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-5-(Trifluoromethyl)Propiophenone, 97 undergoes rigorous analytical testing to ensure it meets the stringent purity and consistency standards required for advanced synthetic applications. Our quality assurance protocols are designed to support cGMP and ISO 9001 compliant manufacturing environments. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, reducing agents, and sources of ignition. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.