Description

6-(1-Fluoro-1-Methyl-Ethyl)-3H-Pyrimidin-4-One is a specialized fluorinated pyrimidinone derivative, a high-value building block in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which is critical for introducing specific fluorinated motifs into target molecules, thereby modulating their biological activity and physicochemical properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially in oncology and antiviral research, where the fluorinated moiety can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine atom to improve efficacy and environmental profile.
• Chemical Biology Probe Development: Acts as a versatile scaffold for creating molecular probes to study enzyme mechanisms and biological pathways.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with unique electronic or surface properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	6-(1-Fluoro-1-Methyl-Ethyl)-3H-Pyrimidin-4-One
CAS No.	240414-09-9
Molecular Formula	C7H9FN2O
Molecular Weight	156.16 g/mol
Synonyms	6-(1-Fluoro-1-methylethyl)-3H-pyrimidin-4-one; 6-(1-Fluoro-1-methylethyl)-4(3H)-pyrimidinone; 4(3H)-Pyrimidinone, 6-(1-fluoro-1-methylethyl)-; 6-(1-Fluoro-1-methylethyl)pyrimidin-4(3H)-one; 6-(1-Fluoro-1-methylethyl)-4-hydroxypyrimidine; 240414-09-9; Fluorinated pyrimidinone intermediate
EINECS	Contact for details

Quality Control

Our 6-(1-Fluoro-1-Methyl-Ethyl)-3H-Pyrimidin-4-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where required, ensuring reliable supply for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.