Description

2-Fluoro-3-(trifluoromethyl)benzylamine is a high-value fluorinated aromatic amine building block. This compound is critical for introducing specific steric and electronic properties into target molecules, enhancing their biological activity and metabolic stability. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atoms contribute to improved lipophilicity and target binding.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers and liquid crystals, where it imparts unique solubility and thermal properties.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules to study protein interactions and cellular processes.

Basic Information

Product Name	2-Fluoro-3-(trifluoromethyl)benzylamine
CAS No.	239135-49-0
Molecular Formula	C8H7F4N
Molecular Weight	193.14 g/mol
Synonyms	(2-Fluoro-3-(trifluoromethyl)phenyl)methanamine; 1-(Aminomethyl)-2-fluoro-3-(trifluoromethyl)benzene; 2-Fluoro-α-(trifluoromethyl)benzylamine; 2-Fluoro-3-trifluoromethylbenzylamine; Benzenemethanamine, 2-fluoro-α-(trifluoromethyl)-; α-(Trifluoromethyl)-2-fluorobenzylamine
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-(trifluoromethyl)benzylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.